A.D.H.D.

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background-image: url("data:image/png;base64,#images/daftpunktocat-thomas.gif")
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.pull-left[

# A.D.H.D.

## Neuropsychological assessment for diagnostic clarification and treatment planning

### Joey Trampush, Ph.D.

### Della Martin Assistant Professor of Psychiatry

### 2021-12-21
]

---
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### .big-text[Hello.]

???

We grew since 2018

---
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.bg-washed-green.b--dark-green.ba.bw2.br3.shadow-5.ph4.mt5[
If you cannot explain something in simple terms, you don't understand it.

.tr[
— Richard Feynman
]]

.center[![:scale 50%](data:image/png;base64,#images/jerry_maguire.gif)]

---
class: left, middle
type: exclaim

What do I know about .big[ADHD]

.right[![:scale 40%](data:image/png;base64,#images/dinotocat.png)]

.footnote[.red.bold[*] Important footnote]

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[<svg aria-hidden="true" role="img" viewBox="0 0 512 512" style="height:1em;width:1em;vertical-align:-0.125em;margin-left:auto;margin-right:auto;font-size:inherit;fill:currentColor;overflow:visible;position:relative;"><path d="M459.37 151.716c.325 4.548.325 9.097.325 13.645 0 138.72-105.583 298.558-298.558 298.558-59.452 0-114.68-17.219-161.137-47.106 8.447.974 16.568 1.299 25.34 1.299 49.055 0 94.213-16.568 130.274-44.832-46.132-.975-84.792-31.188-98.112-72.772 6.498.974 12.995 1.624 19.818 1.624 9.421 0 18.843-1.3 27.614-3.573-48.081-9.747-84.143-51.98-84.143-102.985v-1.299c13.969 7.797 30.214 12.67 47.431 13.319-28.264-18.843-46.781-51.005-46.781-87.391 0-19.492 5.197-37.36 14.294-52.954 51.655 63.675 129.3 105.258 216.365 109.807-1.624-7.797-2.599-15.918-2.599-24.04 0-57.828 46.782-104.934 104.934-104.934 30.213 0 57.502 12.67 76.67 33.137 23.715-4.548 46.456-13.32 66.599-25.34-7.798 24.366-24.366 44.833-46.132 57.827 21.117-2.273 41.584-8.122 60.426-16.243-14.292 20.791-32.161 39.308-52.628 54.253z"/></svg> @brainworkup](https://twitter.com/brainworkup)   
[<svg aria-hidden="true" role="img" viewBox="0 0 512 512" style="height:1em;width:1em;vertical-align:-0.125em;margin-left:auto;margin-right:auto;font-size:inherit;fill:currentColor;overflow:visible;position:relative;"><path d="M326.612 185.391c59.747 59.809 58.927 155.698.36 214.59-.11.12-.24.25-.36.37l-67.2 67.2c-59.27 59.27-155.699 59.262-214.96 0-59.27-59.26-59.27-155.7 0-214.96l37.106-37.106c9.84-9.84 26.786-3.3 27.294 10.606.648 17.722 3.826 35.527 9.69 52.721 1.986 5.822.567 12.262-3.783 16.612l-13.087 13.087c-28.026 28.026-28.905 73.66-1.155 101.96 28.024 28.579 74.086 28.749 102.325.51l67.2-67.19c28.191-28.191 28.073-73.757 0-101.83-3.701-3.694-7.429-6.564-10.341-8.569a16.037 16.037 0 0 1-6.947-12.606c-.396-10.567 3.348-21.456 11.698-29.806l21.054-21.055c5.521-5.521 14.182-6.199 20.584-1.731a152.482 152.482 0 0 1 20.522 17.197zM467.547 44.449c-59.261-59.262-155.69-59.27-214.96 0l-67.2 67.2c-.12.12-.25.25-.36.37-58.566 58.892-59.387 154.781.36 214.59a152.454 152.454 0 0 0 20.521 17.196c6.402 4.468 15.064 3.789 20.584-1.731l21.054-21.055c8.35-8.35 12.094-19.239 11.698-29.806a16.037 16.037 0 0 0-6.947-12.606c-2.912-2.005-6.64-4.875-10.341-8.569-28.073-28.073-28.191-73.639 0-101.83l67.2-67.19c28.239-28.239 74.3-28.069 102.325.51 27.75 28.3 26.872 73.934-1.155 101.96l-13.087 13.087c-4.35 4.35-5.769 10.79-3.783 16.612 5.864 17.194 9.042 34.999 9.69 52.721.509 13.906 17.454 20.446 27.294 10.606l37.106-37.106c59.271-59.259 59.271-155.699.001-214.959z"/></svg> brainworkup.io](https://brainworkup.io)

???

80HD

---
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## Data Science

.left[

![:scale 45%](data:image/png;base64,#images/computer.gif)

]

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.big[1.]

## inattention

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.big[2.]

## hyperactivity

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.big[3.]

## impulsivity

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.big[4.]

## working memory

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.big[5.]

## stimulus boundness

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color: white

##### .big[Clinical ADHD vs Cognitive ADHD]

.pull-left.white[
#### inattention
#### hyperactivity
#### impulsivity
]

.pull-right.white[
#### working memory
#### response variability
#### stimulus boundness
]

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### Neurocognitive deficits related to adhd

.panelset[
.panel[.panel-name[Working Memory]

#### Working Memory

- Remembering things short term memory

- Verbal information

- Nonverbal information

- "mind's eye"
]

.panel[.panel-name[Processing Speed]

#### Processing Speed

- Rate of test taking

- Rate of speed of information processing

- Some other description

- Fourth layer

]

.panel[.panel-name[Response Variability]

#### Response Variability

- Reaction time variability

- Response consistency

- Attentional drift

- Impulsive responding

]

.panel[.panel-name[Inhibitory Control]

#### Inhibitory Control

- Go/No-Go performance

- Core DSM symptom (impulsivity)

- Something else ...

- Impulsive responding

]
]

---
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background-position: 50% 50%
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## Emotional Control

.pull-left[

> **Emotion** 🔥
>
> **(Dys)Regulation**
> 
> **in**
>
> **ADHD:**
> 
> Not part of DSM/ICD diagnostic criteria 
>
> .big[BUT] ...
>
> ... a core feature of the disorder

]

???

This is recognized on most rating scales e.g., brown

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.frame[
### Read these words as fast as you can
]

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.frame[
## RED
]

.frame[
## GREEN
]

.frame[
## BLUE 
]

.frame[
## YELLOW

]

???

This is how we test it

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.frame[
## .red[RED]
]

.frame[
## .green[GREEN]
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.frame[
## .blue[BLUE] 
]

.frame[
## .yellow[YELLOW]
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???

This is how we test it

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## .blue[RED]
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.frame[
## .yellow[GREEN]
]

.frame[
## .red[BLUE] 
]

.frame[
## .green[YELLOW]
]

???

This is how we test it

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# Agenda

The .big-text[name] of this slide is {{ name }}.
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### Distribution of Scores: _Population-level Interpretation_

<div class="figure">
<img src="data:image/png;base64,#images/plot_narrow.png" alt="Statistical classification of neuropsychological test scores in the general population." width="50%" />
<p class="caption">Statistical classification of neuropsychological test scores in the general population.</p>
</div>

---
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### Distribution of Scores: _Clinical Interpretation_

<div class="figure">
<img src="data:image/png;base64,#images/plot_broad.png" alt="General clinical interpretation of performance for individual test scores and broader neuropsychological domains." width="50%" />
<p class="caption">General clinical interpretation of performance for individual test scores and broader neuropsychological domains.</p>
</div>

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### Highcharte`R` Drilldown
### Z-scores (Mean = 0, SD = 1)

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